The rising incidence of chronic diseases is pushing up the requirement for protein expression across the world. Viral diseases like HIV/AIDS, hepatitis, cancer, cardiovascular diseases, and chronic obstructive pulmonary diseases (COPD) are the major types of chronic diseases occurring around the world. As per the World Health Organization (WHO), chronic diseases are responsible for 60.0% of all deaths across the world. These diseases need clinical intervention, in which, the adoption of protein expression methods is growing rapidly.
Moreover, with the surge in geriatric population, the demand for protein expression is growing rapidly around the world. This is because older people require more intense and regular therapies and treatment procedures than younger persons, on account of their higher vulnerability to chronic diseases. As per the United Nations Department of Economic and Social Affairs (UNDESA), the total number of people in the age bracket- 60 years or above is predicted to increase by 56.0% across the world.
In simpler terms, it can be said that the number of geriatric people across the world will rise from 901 million to 1.4 billion from 2015 to 2030, as per the estimates of the UNDESA. The increasing life expectancy and falling birth rates are fueling the growth of the geriatric population all over the world. This is propelling the requirement for protein expression, which is, in turn, driving the advancement of the global protein expression market.
There are mainly six types of protein expression systems namely prokaryotic expression systems, mammalian cell expression systems, algal-based expression systems, yeast expression systems, insect cell expression systems, and cell-free expression systems. Out of these, the usage of the prokaryotic expression systems was found to be the highest during the last few years. This was because these systems are more affordable than the mammalian cell expression and insect cell expression systems.
The biggest end-users of protein expression are contract research organizations, pharmaceutical and biotechnology companies, and academic research institutes. Out of these, the requirement for protein expression is predicted to be the highest in pharmaceutical and biotechnology companies in the forthcoming years. Across the globe, the protein expression market registered the highest growth in North America in the past years, as per the findings of the market research company, P&S Intelligence.
The large-scale adoption of protein expression in this region was due to the high incidence of chronic diseases, the growth and development of research and development (R&D) infrastructure, the rise in healthcare spending, and the presence of a large geriatric population in the region. In this region, the usage of protein expression was the highest in the U.S. in the past. After North America, the adoption of protein expression was the highest in Europe in the years gone by.
Hence, it is safe to say that the demand for protein expression is predicted to soar all over the world in the coming years, primarily because of the growing prevalence of chronic diseases, the surging population of geriatric people, and rapid technological advancements being made in protein-based research.